Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 1.00 |
| ▸ | KLK1 | P06870 | 3/20 | 1.00 |
| ▸ | F2 | P00734 | 6/20 | 0.85 |
| ▸ | F10 | P00742 | 6/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14688600 | 0.95 | KLKB1 (0.91) | KLKB1KLK1F2F10 | |
| SCHEMBL14688287 | 0.94 | KLKB1 (0.89) | KLKB1KLK1F2F10 | |
| SCHEMBL2547690 | 0.93 | KLKB1 (0.87) | KLKB1KLK1F2F10 | |
| SCHEMBL14845921 | 0.93 | KLKB1 (1.00) | KLKB1KLK1F2F10 | |
| SCHEMBL20506370 | 0.92 | KLKB1 (1.00) | KLKB1KLK1F2F10 | |
| SCHEMBL14688741 | 0.92 | KLKB1 (0.85) | KLKB1KLK1F2F10 | |
| SCHEMBL14688308 | 0.92 | KLKB1 (0.85) | KLKB1KLK1F2F10 | |
| SCHEMBL2551329 | 0.91 | KLKB1 (0.83) | KLKB1KLK1F2F10 | |
| SCHEMBL14688297 | 0.91 | KLKB1 (0.83) | KLKB1KLK1F2F10 | |
| SCHEMBL2550221 | 0.91 | KLKB1 (0.82) | KLKB1KLK1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049591-A2 | DUAL INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | VERSEON CORPORATION (US) | 2013-04-04 | — | — | WO | claimed |
| EP-3421036-B1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON CORP (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3421036-A1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | Verseon Corporation (US) | 2019-01-02 | — | — | EP | disclosed |
| EP-2968297-B1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON CORP (US) | 2018-09-26 | — | — | EP | disclosed |
| WO-2013049591-A2 | DUAL INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | VERSEON CORPORATION (US) | 2013-04-04 | — | — | WO | disclosed |