Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.51 |
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | UBE2M | P61081 | 2/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14834179 | 0.88 | EPHX1 (0.56) | EPHX2MGLLEPHX1USP30 | |
| SCHEMBL14834217 | 0.85 | EPHX2 (0.61) | EPHX2MGLLMEN1KMT2AUBE2M | |
| SCHEMBL14834256 | 0.85 | EPHX2 (0.57) | EPHX2MGLLKMT2AEPHX1ALDH1A1 | |
| SCHEMBL14834365 | 0.83 | EPHX2 (0.52) | EPHX2MEN1KMT2AUBE2MDCUN1D1 | |
| SCHEMBL6582812 | 0.83 | CA12 (0.56) | EPHX2CCNCCDK8MEN1KMT2A | |
| SCHEMBL14834371 | 0.83 | EPHX2 (0.53) | EPHX2MGLLMEN1KMT2AUBE2M | |
| SCHEMBL7423886 | 0.79 | EPHX2 (0.52) | EPHX2CCNCCDK8MEN1KMT2A | |
| SCHEMBL14834327 | 0.79 | EPHX2 (0.58) | EPHX2MGLLEPHX1ALDH1A1USP30 | |
| SCHEMBL14834198 | 0.75 | SYK (0.44) | MGLL | |
| SCHEMBL14834002 | 0.75 | EPHX2 (0.47) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576507-B1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2017-04-05 | — | — | EP | disclosed |
| EP-2576507-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011151808-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2011-12-08 | — | — | WO | disclosed |