Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938637 | 0.87 | TTK (0.76) | TTK | |
| SCHEMBL9937820 | 0.83 | TTK (0.72) | TTK | |
| SCHEMBL9938006 | 0.83 | TTK (0.71) | TTK | |
| SCHEMBL9936990 | 0.82 | TTK (0.70) | TTK | |
| SCHEMBL14834597 | 0.79 | TTK (1.00) | TTK | |
| SCHEMBL14834723 | 0.75 | TTK (1.00) | TTK | |
| SCHEMBL9966176 | 0.75 | TTK (0.59) | TTK | |
| SCHEMBL14834436 | 0.74 | TTK (1.00) | TTK | |
| SCHEMBL9966501 | 0.72 | TTK (0.72) | TTK | |
| SCHEMBL14834733 | 0.71 | TTK (1.00) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199999-B2 | Substituted imidazopyrazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | claimed |
| EP-2576560-B1 | SUBSTITUTED IMIDAZOPYRAZINES | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | claimed |
| US-20130210815-A1 | SUBSTITUTED IMIDAZOPYRAZINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-15 | — | — | US | claimed |
| EP-2576560-A1 | SUBSTITUTED IMIDAZOPYRAZINES | Bayer Intellectual Property GmbH (DE) | 2013-04-10 | — | — | EP | claimed |
| WO-2011151259-A1 | SUBSTITUTED IMIDAZOPYRAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-08 | — | — | WO | claimed |
| US-9199999-B2 | Substituted imidazopyrazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9199999-B2 | Substituted imidazopyrazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2576560-B1 | SUBSTITUTED IMIDAZOPYRAZINES | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| EP-2576560-B1 | SUBSTITUTED IMIDAZOPYRAZINES | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-20130210815-A1 | SUBSTITUTED IMIDAZOPYRAZINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2011151259-A1 | SUBSTITUTED IMIDAZOPYRAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210815-A1 | SUBSTITUTED IMIDAZOPYRAZINES | CYP3A5, CYP3A43, HRH2 | TTK 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.