Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 17/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20957467 | 1.00 | GPBAR1 (0.64) | GPBAR1PRKCDNR1H4 | |
| SCHEMBL9107282 | 1.00 | GPBAR1 (0.64) | GPBAR1PRKCDNR1H4 | |
| SCHEMBL17794080 | 1.00 | GPBAR1 (0.64) | GPBAR1PRKCDNR1H4 | |
| SCHEMBL19487670 | 1.00 | GPBAR1 (0.64) | GPBAR1PRKCDNR1H4 | |
| SCHEMBL9103404 | 0.93 | NR1H4 (0.58) | GPBAR1PRKCDNR1H4 | |
| SCHEMBL9107407 | 0.92 | GPBAR1 (0.68) | GPBAR1PRKCD | |
| SCHEMBL16510620 | 0.92 | GPBAR1 (0.68) | GPBAR1PRKCD | |
| SCHEMBL18133095 | 0.92 | GPBAR1 (0.68) | GPBAR1PRKCD | |
| SCHEMBL20994179 | 0.92 | GPBAR1 (0.68) | GPBAR1PRKCD | |
| SCHEMBL14682833 | 0.91 | GPBAR1 (0.67) | GPBAR1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576586-A1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | Bristol-Myers Squibb Company (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011153319-A1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-12-08 | — | — | WO | disclosed |