⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31280032 | 0.71 | — | — | |
| SCHEMBL5212218 | 0.61 | — | — | |
| SCHEMBL4472991 | 0.55 | — | — | |
| SCHEMBL30148658 | 0.54 | — | — | |
| SCHEMBL8669889 | 0.51 | — | — | |
| SCHEMBL27806675 | 0.46 | — | — | |
| SCHEMBL30037272 | 0.41 | — | — | |
| SCHEMBL9172246 | 0.41 | — | — | |
| SCHEMBL561115 | 0.41 | — | — | |
| SCHEMBL15751096 | 0.39 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507481-B2 | Benzoxazine oxazolidinone compounds, preparation methods and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2013-08-13 | — | — | US | disclosed |
| CN-102260277-B | Novel benzoxazine oxazolidinone compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2013-07-24 | — | — | CN | disclosed |
| US-20130123249-A1 | NOVEL BENZOXAZINE OXAZOLIDINONE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | NANJING CHANGAO PHARMACEUTICAL SCIENCE & TECHNOLOGY CO., LIMITED (CN) | 2013-05-16 | — | — | US | disclosed |
| EP-2578591-A1 | NOVEL BENZOXAZINE OXAZOLIDINONE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | Shanghai Institute Materia Medica, Chinese Academy Of Sciences (CN) | 2013-04-10 | — | — | EP | disclosed |
| CN-102260277-A | Novel benzoxazine oxazolidinone compound and preparation method and application thereof | — | 2011-11-30 | — | — | CN | disclosed |