Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.47 |
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14837228 | 0.86 | GRIN1 (0.48) | CNR2GRIN1GRIN2BRHEBNPC1 | |
| SCHEMBL8037413 | 0.85 | MAPT (0.52) | CNR2GRIN1GRIN2BRHEBNPC1 | |
| SCHEMBL14837303 | 0.85 | GRIN1 (0.47) | CNR2GRIN1GRIN2BRHEBNPC1 | |
| Hydrochloric Acid SCHEMBL11903470 | 0.82 | GRIN1 (0.47) | CNR2GRIN1GRIN2BRHEBNPC1 | |
| SCHEMBL23280058 | 0.81 | GRIN1 (0.58) | CNR2GRIN1GRIN2BRHEBNPC1 | |
| SCHEMBL1100174 | 0.81 | GRIN1 (0.70) | GRIN1GRIN2BNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11903446 | 0.81 | GRIN1 (0.52) | CNR2GRIN1GRIN2BNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11903592 | 0.81 | GAA (0.56) | GRIN1GRIN2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14837394 | 0.80 | GRIN1 (0.60) | GRIN1GRIN2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4164834 | 0.79 | GAA (0.66) | GRIN1GRIN2BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578573-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA Eiyo Ltd. (JP) | 2013-04-10 | — | — | EP | claimed |
| EP-2578573-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA Eiyo Ltd. (JP) | 2013-04-10 | — | — | EP | disclosed |