Furaltadone

Furaltadone

SCHEMBL14837124

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1.O=C1OC(CN2CCOCC2)CN1N=Cc1ccc([N+](=O)[O-])o1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.84
HIF1A Q16665 2/20 0.84
USP2 O75604 1/20 0.84
MAPK9 P45984 1/20 0.84
LMNA P02545 7/20 0.66
MAPT P10636 6/20 0.66
TP53 P04637 5/20 0.66
TDP1 Q9NUW8 4/20 0.66
MDM2 Q00987 4/20 0.66
CYP1A2 P05177 3/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
CYP3A4 P08684 2/20 0.66
CISD1 Q9NZ45 2/20 0.66
KDM4E B2RXH2 2/20 0.66
ABCC4 O15439 1/20 0.66
TSHR P16473 1/20 0.66
MAOA P21397 1/20 0.66
CASP7 P55210 1/20 0.66
HSD17B10 Q99714 1/20 0.66
ALDH1A1 P00352 6/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Levofuraltadone SCHEMBL29577077 0.92 HIF1A (1.00) KMT2AHIF1AUSP2MAPK9LMNA
Furaltadone SCHEMBL49268 0.92 HIF1A (1.00) KMT2AHIF1AUSP2MAPK9LMNA
Furaltadone SCHEMBL49267 0.92 HIF1A (1.00) KMT2AHIF1AUSP2MAPK9LMNA
Furaltadone SCHEMBL11742110 0.92 HIF1A (1.00) KMT2AHIF1AUSP2MAPK9LMNA
Furaltadone SCHEMBL49269 0.92 HIF1A (1.00) KMT2AHIF1AUSP2MAPK9LMNA
Furaltadone SCHEMBL2585605 0.91 HIF1A (0.98) KMT2AHIF1AUSP2MAPK9LMNA
Furaltadone SCHEMBL2585607 0.91 HIF1A (0.98) KMT2AHIF1AUSP2MAPK9LMNA
SCHEMBL30869093 0.83 KMT2A (0.82) KMT2AHIF1AUSP2MAPK9LMNA
SCHEMBL32691021 0.83 KMT2A (0.82) KMT2AHIF1AUSP2MAPK9LMNA
SCHEMBL32690884 0.81 HIF1A (0.79) KMT2AHIF1AUSP2MAPK9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2578209-B1 NANOPARTICULATE COMPOSITION CONTAINING ANTIBIOTICS FOR INTRAMAMMARY ADMINISTRATION IN ANIMALS UNIV FEDERAL OURO PRETO (BR) 2019-08-07 EP disclosed
US-10098840-B2 Nanoparticulate composition containing antibiotics for intramammary administration in animals UNIVERSIDADE FEDERAL DE OURO PRETO (BR) 2018-10-16 US disclosed
US-20130189368-A1 NANOPARTICULATE COMPOSITION CONTAINING ANTIBIOTICS FOR INTRAMAMMARY ADMINISTRATION IN ANIMALS UNIVERSIDADE FEDERAL DE OURO PRETO (BR) 2013-07-25 US disclosed
EP-2578209-A1 NANOPARTICULATE COMPOSITION CONTAINING ANTIBIOTICS FOR INTRAMAMMARY ADMINISTRATION IN ANIMALS Universidade Federal De Ouro Preto (BR) 2013-04-10 EP disclosed