Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 12/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402638 | 0.90 | ACKR3 (0.48) | ACKR3NPSR1ALDH1A1 | |
| SCHEMBL402891 | 0.90 | ACKR3 (0.48) | ACKR3NPSR1ALDH1A1 | |
| SCHEMBL29714045 | 0.89 | ACKR3 (0.51) | ACKR3NPSR1CSF1R | |
| SCHEMBL402357 | 0.89 | ACKR3 (0.51) | ACKR3NPSR1CSF1R | |
| SCHEMBL3215386 | 0.89 | ACKR3 (0.51) | ACKR3NPSR1CSF1R | |
| SCHEMBL3211931 | 0.89 | ACKR3 (0.51) | ACKR3NPSR1CSF1R | |
| SCHEMBL403312 | 0.89 | ACKR3 (0.51) | ACKR3NPSR1CSF1R | |
| SCHEMBL399132 | 0.87 | ACKR3 (0.49) | ACKR3NPSR1CSF1R | |
| SCHEMBL401365 | 0.87 | ACKR3 (0.49) | ACKR3NPSR1CSF1R | |
| SCHEMBL401351 | 0.86 | ACKR3 (0.49) | ACKR3EPHX2NPSR1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959960-B1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2013-04-10 | — | — | EP | disclosed |