Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GMNN | O75496 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581295 | 0.97 | MAPK1 (0.58) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL11584970 | 0.97 | MAPK1 (0.58) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL11581266 | 0.97 | MAPK1 (0.58) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL1483375 | 0.97 | MAPK1 (0.58) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL11787560 | 0.95 | MAPK1 (0.57) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL1484416 | 0.95 | MAPK1 (0.51) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL15216484 | 0.91 | MAPK1 (0.53) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL15216420 | 0.91 | MAPK1 (0.53) | MAPK1MAPTLMNAALDH1A1PRKCA | |
| SCHEMBL15216416 | 0.91 | MAPK1 (0.53) | MAPK1MAPTLMNAALDH1A1MEN1 | |
| SCHEMBL15216421 | 0.91 | MAPK1 (0.53) | MAPK1MAPTLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110082118-A1 | Onychomycosis Treatment Delivery System | PRUGEN IP HOLDINGS, INC | 2011-04-07 | — | — | US | disclosed |
| US-20110076261-A1 | Antifungal Drug Delivery System | PRUGEN IP HOLDINGS, INC | 2011-03-31 | — | — | US | disclosed |
| EP-2166837-A1 | DRUG COMBINATION FOR THE TREATMENT OF SKIN DISORDERS | Prugen, Inc. (US) | 2010-03-31 | — | — | EP | disclosed |
| US-20080317737-A1 | Drug combination for the treatment of skin disorders | PRUGEN, INC. | 2008-12-25 | — | — | US | disclosed |
| WO-2008156798-A1 | DRUG COMBINATION FOR THE TREATMENT OF SKIN DISORDERS | PRUGEN, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| US-4292035-A | COMPLEX OF SMECTITE CLAYS, AMINES, AND ORGANIC SULFONIUM, PHOSPHONIUM, OR QUATERNARY AMMONIUM COMPOUNDS, WITH AN ANIONIC SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-4174291-A | DETERGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4101455-A | Low phosphate content glassy phosphate detergent compositions having optimum detergency | THE PROCTER & GAMBLE COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
| US-4062647-A | Clay-containing fabric softening detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-4051046-A | ANTISTATIC AGENTS, SOFTENERS, WRINKLE RESISTANCE | THE PROCTER & GAMBLE COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4000080-A | ETHYLENE OXIDE CONDENSATION PRODUCT WITH MALEIC ANHYDRIDE-VINYL METHYL ETHER COPOLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1976-12-28 | — | — | US | disclosed |