Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910603 | 0.81 | SYK (0.72) | SYKKCNH2AURKB | |
| SCHEMBL14839138 | 0.74 | SYK (0.74) | SYKAURKB | |
| SCHEMBL14839007 | 0.73 | SYK (0.72) | SYKKCNH2AURKB | |
| SCHEMBL16743159 | 0.72 | SYK (0.71) | SYKKCNH2AURKB | |
| SCHEMBL16743186 | 0.72 | SYK (0.71) | SYKKCNH2AURKB | |
| SCHEMBL16743317 | 0.71 | SYK (0.71) | SYKKCNH2AURKB | |
| SCHEMBL16743166 | 0.71 | SYK (0.73) | SYKKCNH2AURKB | |
| SCHEMBL14838986 | 0.70 | SYK (1.00) | SYKKCNH2AURKB | |
| SCHEMBL14839216 | 0.70 | SYK (1.00) | SYKKCNH2AURKB | |
| SCHEMBL14839149 | 0.70 | SYK (0.86) | SYKKCNH2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013047813-A1 | 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE | 大鵬薬品工業株式会社 (JP) | 2013-04-04 | — | — | WO | disclosed |