Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839030 | 0.90 | SYK (1.00) | SYKKCNH2 | |
| SCHEMBL14838967 | 0.88 | SYK (0.80) | SYK | |
| SCHEMBL15935600 | 0.87 | SYK (0.87) | SYKKCNH2 | |
| SCHEMBL14839175 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL15910748 | 0.86 | SYK (1.00) | SYKKCNH2 | |
| SCHEMBL15910589 | 0.85 | SYK (0.98) | SYKKCNH2 | |
| SCHEMBL16253403 | 0.84 | SYK (0.81) | SYKKCNH2 | |
| SCHEMBL15935564 | 0.84 | SYK (0.74) | SYKKCNH2 | |
| Hydrochloric Acid SCHEMBL15910632 | 0.83 | SYK (0.79) | SYKKCNH2 | |
| SCHEMBL15910612 | 0.81 | SYK (0.79) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2762476-A1 | 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE | Taiho Pharmaceutical Co., Ltd. (JP) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013047813-A1 | 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE | 大鵬薬品工業株式会社 (JP) | 2013-04-04 | — | — | WO | disclosed |