Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839165 | 0.97 | SYK (0.61) | SYKKDRAURKB | |
| SCHEMBL14839103 | 0.82 | SYK (0.65) | SYKKDRAURKBKCNH2 | |
| SCHEMBL15935646 | 0.81 | SYK (0.71) | SYK | |
| SCHEMBL15910592 | 0.79 | SYK (1.00) | SYKKDRAURKB | |
| SCHEMBL14839148 | 0.79 | SYK (0.77) | SYKKDRAURKB | |
| SCHEMBL16253442 | 0.76 | SYK (0.65) | SYKKDRAURKB | |
| SCHEMBL15935613 | 0.76 | SYK (0.94) | SYKKDRAURKB | |
| SCHEMBL16142232 | 0.72 | SYK (0.57) | SYKKDRAURKBKCNH2 | |
| SCHEMBL14839171 | 0.71 | SYK (0.63) | SYKKDRAURKB | |
| SCHEMBL16743210 | 0.69 | SYK (0.61) | SYKKDRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013047813-A1 | 1,2,4-TRIAZINE-6-CARBOXAMIDE DERIVATIVE | 大鵬薬品工業株式会社 (JP) | 2013-04-04 | — | — | WO | disclosed |