Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731685 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL729461 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL731397 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL17851227 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL729056 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL1897662 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL17851220 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL729433 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL731354 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 | |
| SCHEMBL17851210 | 0.98 | TSHR (0.76) | TSHRHPGDCYP3A4ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| EP-2295479-B1 | COPOLYMER, METHOD FOR PRODUCING THE SAME, OIL REPELLENT COMPOSITION AND ARTICLE PROCESSED WITH THE OIL REPELLENT COMPOSITION | ASAHI GLASS CO LTD (JP) | 2015-02-11 | — | — | EP | disclosed |
| US-8431664-B2 | Copolymer, method for its production, oil repellent composition and article treated therewith | ASAHI GLASS COMPANY, LIMITED (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20110077349-A1 | COPOLYMER, METHOD FOR ITS PRODUCTION, OIL REPELLENT COMPOSITION AND ARTICLE TREATED THEREWITH | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-03-31 | — | — | US | disclosed |
| EP-2295479-A1 | COPOLYMER, METHOD FOR PRODUCING THE SAME, OIL REPELLENT COMPOSITION AND ARTICLE PROCESSED WITH THE OIL REPELLENT COMPOSITION | Asahi Glass Company, Limited (JP) | 2011-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242548-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | KRAS, HRAS, NRAS | TSHR 4752/4885HPGD 1795/4885CYP3A4 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.