Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14843174 | 0.92 | PDE10A (0.53) | PDE10A | |
| SCHEMBL14842847 | 0.88 | PDE10A (0.55) | PDE10A | |
| SCHEMBL14843161 | 0.87 | PDE10A (0.52) | PDE10A | |
| SCHEMBL14843494 | 0.86 | PDE10A (0.57) | PDE10A | |
| SCHEMBL14843105 | 0.85 | PDE10A (0.56) | PDE10A | |
| SCHEMBL14853981 | 0.84 | PDE10A (0.56) | PDE10A | |
| SCHEMBL14843077 | 0.83 | PDE10A (0.50) | PDE10A | |
| SCHEMBL14842849 | 0.82 | PDE10A (0.53) | PDE10A | |
| SCHEMBL14842886 | 0.81 | PDE10A (0.57) | PDE10A | |
| SCHEMBL14843112 | 0.81 | PDE10A (0.52) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013050527-A1 | QUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2013-04-11 | — | — | WO | claimed |
| WO-2013050527-A1 | QUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2013-04-11 | — | — | WO | disclosed |