Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15562802 | 0.87 | FFAR1 (0.35) | — | |
| SCHEMBL24732113 | 0.75 | CYP19A1 (0.32) | — | |
| SCHEMBL23387 | 0.72 | NOTUM (0.33) | — | |
| SCHEMBL31569257 | 0.67 | HTR2C (0.37) | — | |
| SCHEMBL7293522 | 0.67 | SLC6A4 (0.61) | — | |
| Hydrochloric Acid SCHEMBL7293026 | 0.66 | SLC6A4 (0.59) | — | |
| SCHEMBL3829652 | 0.64 | HTR2C (0.47) | — | |
| SCHEMBL2897892 | 0.62 | POLB (0.45) | — | |
| SCHEMBL5190567 | 0.62 | POLB (0.50) | — | |
| SCHEMBL2919209 | 0.62 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788351-A1 | SUBSTITUTED 3,4-DIHYDROPYRROLO[1,2-a]PYRAZIN-1(2H)-ONE DERIVATIVES AS KINASES INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013050446-A1 | SUBSTITUTED 3,4-DIHYDROPYRROLO[1,2-a]PYRAZIN-1(2H)-ONE DERIVATIVES AS KINASES INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2013-04-11 | — | — | WO | disclosed |