Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844368 | 1.00 | GAA (0.48) | GAANFKB1NFKB2RELASCN9A | |
| SCHEMBL2010969 | 0.85 | GAA (0.51) | GAANFKB1NFKB2RELACTSK | |
| SCHEMBL2010967 | 0.85 | GAA (0.51) | GAANFKB1NFKB2RELACTSK | |
| SCHEMBL2015566 | 0.84 | GAA (0.47) | GAANFKB1NFKB2RELASCN9A | |
| SCHEMBL12274513 | 0.84 | GAA (0.47) | GAANFKB1NFKB2RELASCN9A | |
| SCHEMBL2011320 | 0.83 | GAA (0.49) | GAANFKB1NFKB2RELACTSK | |
| SCHEMBL2011317 | 0.83 | GAA (0.49) | GAANFKB1NFKB2RELACTSK | |
| SCHEMBL9908799 | 0.81 | GAA (0.47) | GAANFKB1NFKB2RELACTSK | |
| SCHEMBL4760849 | 0.81 | GAA (0.47) | GAANFKB1NFKB2RELACTSK | |
| SCHEMBL23571245 | 0.80 | CYP11B1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763970-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050302-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-11 | — | — | WO | disclosed |