SCHEMBL14845477

COCCNC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCCN)NC(=O)CSC

nearest known ligand 0.54

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	16/20	0.54

▸	OPRL1	P41146	2/20	0.47

▸	TFPI	P10646	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11933674	0.96	IL23R (0.55)	IL23R
SCHEMBL11988608	0.93	IL23R (0.52)	IL23ROPRL1TFPI
SCHEMBL15296277	0.91	IL23R (0.58)	IL23R
SCHEMBL10046407	0.91	IL23R (0.58)	IL23R
SCHEMBL13532019	0.86	IL23R (0.59)	IL23R
SCHEMBL16727688	0.85	IL23R (0.53)	IL23R
SCHEMBL13703199	0.85	IL23R (0.51)	IL23ROPRL1
SCHEMBL22382220	0.85	IL23R (0.51)	IL23ROPRL1
SCHEMBL14845478	0.85	IL23R (0.48)	IL23R
SCHEMBL16325450	0.84	IL23R (0.55)	IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8415510-B2	Synthesis of a PEG-6 moiety from commercial low-cost chemicals	GE HEALTHCARE LIMITED (GB)	2013-04-09	—	—	US	disclosed