Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14823445 | 0.74 | CA12 (0.42) | CA12CA2CA9TSHRMAPT | |
| SCHEMBL13617936 | 0.69 | S1PR1 (0.54) | S1PR1S1PR3S1PR2LPAR2THRA | |
| SCHEMBL20313356 | 0.69 | CA12 (0.51) | CA12CA2CA9TSHRMEN1 | |
| SCHEMBL29173835 | 0.67 | S1PR1 (0.52) | CA12CA2CA9S1PR1S1PR3 | |
| SCHEMBL29173822 | 0.67 | S1PR1 (0.52) | CA12CA2CA9S1PR1S1PR3 | |
| SCHEMBL30746857 | 0.67 | S1PR1 (0.52) | CA12CA2CA9S1PR1S1PR3 | |
| SCHEMBL29173826 | 0.67 | S1PR1 (0.52) | CA12CA2CA9S1PR1S1PR3 | |
| SCHEMBL20313355 | 0.65 | CA12 (0.47) | CA12CA2CA9TSHRMEN1 | |
| SCHEMBL27944125 | 0.64 | HSD17B3 (0.62) | TP53CYP3A4KDM4EHSD17B10HSD17B3 | |
| SCHEMBL28209780 | 0.64 | HSD17B3 (0.62) | TP53CYP3A4KDM4EHSD17B10HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415446-B2 | Cardanol based dimers and uses therefor | Carolite Corporation (US) | 2013-04-09 | — | — | US | disclosed |