Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL249748 | 0.82 | PDE3B (0.43) | PDE3BPDE3ARORCPSMB5IDO1 | |
| SCHEMBL10232859 | 0.82 | PDE3B (0.43) | PDE3BPDE3ARORCPSMB5IDO1 | |
| SCHEMBL3902905 | 0.82 | PDE3B (0.43) | PDE3BPDE3ARORCPSMB5CETP | |
| SCHEMBL14845785 | 0.81 | IDH2 (0.38) | PDE3BPDE3ARORC | |
| SCHEMBL22077867 | 0.79 | PDE3B (0.46) | PDE3BPDE3ARORCPSMB5IDO1 | |
| SCHEMBL22077865 | 0.79 | PDE3B (0.46) | PDE3BPDE3ARORCPSMB5IDO1 | |
| SCHEMBL22083877 | 0.76 | PDE3B (0.43) | PDE3BPDE3ARORCPSMB5IDO1 | |
| SCHEMBL31395110 | 0.76 | PDE3B (0.44) | PDE3BPDE3ACLCN2PSMB5CETP | |
| SCHEMBL15156704 | 0.76 | PSMB5 (0.50) | PDE3BPDE3APSMB5CETPPTGS2 | |
| SCHEMBL31395020 | 0.74 | PDE3B (0.38) | PDE3BPDE3APSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-B1 | NAPHTHYRIDINE DERIVATIVES HAVING BRONCHODILATING ACTIVITY | RESPIRATORIUS AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| US-8415333-B2 | Bronchodilating diazaheteroaryls | RESPIRATORIOUS AB (SE) | 2013-04-09 | — | — | US | disclosed |