Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14847467 | 0.91 | USP2 (0.48) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14847471 | 0.89 | ABCB1 (0.46) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14769029 | 0.87 | USP2 (0.59) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14847591 | 0.86 | ABCB1 (0.59) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14847509 | 0.85 | ABCB1 (0.45) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14847470 | 0.85 | ABCB1 (0.46) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14847584 | 0.84 | USP2 (0.47) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14847469 | 0.83 | ABCB1 (0.43) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14771619 | 0.81 | USP2 (0.56) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL31344171 | 0.80 | USP2 (0.60) | ABCB1USP2ATMCFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578694-A1 | FLUORESCENT SUBSTRATE FOR DETECTION OF ENZYMATIC ACTIVITY OF NITRILE-RELATED ENZYME | Mitsubishi Rayon Co., Ltd. (JP) | 2013-04-10 | — | — | EP | disclosed |