Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13331738 | 0.91 | SLC5A2 (0.51) | TP53LMNASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2493076 | 0.87 | TP53 (0.73) | TP53LMNASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2497313 | 0.87 | TP53 (0.63) | TP53LMNASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2497214 | 0.87 | TP53 (0.63) | TP53LMNASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2472980 | 0.83 | TP53 (0.58) | TP53LMNASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2495532 | 0.83 | TP53 (0.70) | TP53LMNASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2499433 | 0.83 | TP53 (0.63) | TP53LMNASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2472842 | 0.81 | TP53 (0.55) | TP53ALDH1A1SLC5A2 | |
| SCHEMBL2472264 | 0.81 | TP53 (0.58) | TP53LMNASMN1; SMN2MITFALDH1A1 | |
| SCHEMBL2495408 | 0.81 | TP53 (0.67) | TP53LMNASMN1; SMN2MITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373629-B1 | COMPOUNDS FOR TREATING CANCER | BOEHRINGER INGELHEIM INT (DE) | 2013-04-10 | — | — | EP | disclosed |