Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | MTOR | P42345 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | MLNR | O43193 | 1/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340495 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL17449193 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL10041959 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL10041958 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL14094856 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL18888709 | 0.88 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL10050929 | 0.88 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL26822591 | 0.85 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL15249579 | 0.81 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| Desmethylsertraline SCHEMBL4570539 | 0.81 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3570814-B1 | MOLECULAR ADJUVANTS FOR ENHANCED CYTOSOLIC DELIVERY OF ACTIVE AGENTS | UNIV GENT (BE) | 2023-11-29 | — | — | EP | disclosed |
| WO-2018144385-A1 | ENAMIDE PROCESS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-08-09 | — | — | WO | disclosed |
| EP-2760839-B1 | PYRIDINEDIONE CARBOXAMIDE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL MYERS SQUIBB CO (US) | 2015-11-25 | — | — | EP | disclosed |
| WO-2013049104-A1 | PYRIDINEDIONE CARBOXAMIDE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | WO | disclosed |