SCHEMBL14848985

SCHEMBL14848985

CCc1cc(OCCc2nc(-c3ccc(C)cc3)oc2C)ccc1CCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 20/20 1.00
▸ PPARA Q07869 19/20 1.00
▸ PPARD Q03181 7/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14841186 0.93 PPARG (1.00) PPARGPPARAPPARD
SCHEMBL20235377 0.93 PPARG (0.87) PPARGPPARAPPARD
SCHEMBL14848995 0.91 PPARG (0.84) PPARGPPARAPPARD
SCHEMBL14848993 0.91 PPARG (0.82) PPARGPPARAPPARD
SCHEMBL14849086 0.91 PPARG (1.00) PPARGPPARAPPARD
SCHEMBL20232431 0.90 PPARG (0.82) PPARGPPARAPPARD
SCHEMBL14851137 0.90 PPARG (1.00) PPARGPPARAPPARD
SCHEMBL14851133 0.90 PPARG (0.81) PPARGPPARAPPARD
SCHEMBL14849073 0.89 PPARG (0.80) PPARGPPARAPPARD
SCHEMBL4895550 0.89 PPARG (0.79) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018102399-A1 METHODS OF DOSE ADMINISTRATION FOR TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES T3D THERAPEUTICS, INC. (US) 2018-06-07 — — WO disclosed
US-9346770-B2 Compounds having activating effect on subtypes of peroxisome proliferator-activated receptors and its preparation method and uses ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2016-05-24 — — US disclosed
US-9346770-B2 Compounds having activating effect on subtypes of peroxisome proliferator-activated receptors and its preparation method and uses ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2016-05-24 — — US disclosed
US-20130089613-A1 Compounds Having Activating Effect on Subtypes of Peroxisome Proliferator-Activated Receptors and its Preparation Method and Uses ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2013-04-11 — — US disclosed
US-20130089613-A1 Compounds Having Activating Effect on Subtypes of Peroxisome Proliferator-Activated Receptors and its Preparation Method and Uses ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) 2013-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130089613-A1 Compounds Having Activating Effect on Subtypes of Peroxisome Proliferator-Activated Receptors and its Preparation Method and Uses PPARA, PPARG, PPARD PPARG 2/4885PPARA 1/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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