Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MST1R | Q04912 | 16/20 | 0.59 |
| ▸ | MET | P08581 | 4/20 | 0.58 |
| ▸ | KDR | P35968 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839978 | 0.93 | MST1R (0.62) | MST1RMETKDR | |
| SCHEMBL14849131 | 0.93 | MST1R (0.59) | MST1RMETKDR | |
| SCHEMBL14849168 | 0.92 | MST1R (0.62) | MST1RMETKDR | |
| SCHEMBL14839977 | 0.92 | MST1R (0.66) | MST1RMETKDR | |
| SCHEMBL2537128 | 0.90 | MST1R (0.65) | MST1RMETKDR | |
| SCHEMBL14851260 | 0.89 | MST1R (0.59) | MST1RMETKDR | |
| SCHEMBL14849170 | 0.88 | MST1R (0.61) | MST1RMETKDR | |
| SCHEMBL2534196 | 0.88 | MST1R (0.62) | MST1RMETKDR | |
| SCHEMBL12251147 | 0.86 | MST1R (0.59) | MST1RMETKDR | |
| SCHEMBL2533404 | 0.86 | MST1R (0.59) | MST1RMETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090327-A1 | Inhibitors of Protein Tyrosine Kinase Activity | METHYLGENE INC. (CA) | 2013-04-11 | — | — | US | disclosed |
| US-20130090327-A1 | Inhibitors of Protein Tyrosine Kinase Activity | METHYLGENE INC. (CA) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090327-A1 | Inhibitors of Protein Tyrosine Kinase Activity | KDR, FLT1, FLT4 | MST1R 42/4885MET 25/4885KDR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.