Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14864778 | 1.00 | MME (0.32) | MMEROCK2ROCK1ACACBITGA4 | |
| SCHEMBL8911903 | 0.86 | ACACB (0.33) | MMEACACBITGA4ITGB7ALDH1A1 | |
| SCHEMBL888696 | 0.86 | ACACB (0.33) | MMEACACBITGA4ITGB7ALDH1A1 | |
| SCHEMBL10122822 | 0.86 | ACACB (0.33) | MMEACACBITGA4ITGB7ALDH1A1 | |
| SCHEMBL14886286 | 0.86 | MME (0.31) | MMEACACBITGA4ITGB7 | |
| SCHEMBL10120407 | 0.85 | MME (0.31) | MMEACACBITGA4ITGB7 | |
| SCHEMBL17641845 | 0.82 | — | — | |
| SCHEMBL19487728 | 0.78 | — | — | |
| SCHEMBL13187470 | 0.77 | ITGB2 (0.49) | ALDH1A1 | |
| SCHEMBL12824382 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400846-B1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARM INC (US) | 2016-10-05 | — | — | EP | disclosed |
| WO-2013052362-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2013-04-11 | — | — | WO | disclosed |