Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 6/20 | 0.73 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.73 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.73 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.73 |
| ▸ | SRC | P12931 | 1/20 | 0.73 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.68 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.68 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.68 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.68 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29995120 | 0.93 | P2RY1 (0.74) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL13853911 | 0.93 | P2RY1 (0.74) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL10295499 | 0.91 | P2RY1 (0.71) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL5560007 | 0.90 | P2RY1 (0.91) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL22652873 | 0.90 | P2RY1 (0.91) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL13548820 | 0.90 | P2RY1 (0.91) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL13853893 | 0.90 | P2RY1 (0.91) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL18022428 | 0.90 | P2RY1 (0.91) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL13550314 | 0.90 | P2RY1 (0.91) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 | |
| SCHEMBL14853625 | 0.90 | P2RY1 (0.72) | P2RY1P2RX3P2RY2P2RX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013052523-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | modeRNA Therapeutics (US) | 2013-04-11 | — | — | WO | disclosed |