Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 17/20 | 0.58 |
| ▸ | GAK | O14976 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14864936 | 0.94 | EGFR (0.61) | EGFRERBB2GAK | |
| SCHEMBL14864938 | 0.87 | EGFR (0.59) | EGFRERBB2GAK | |
| SCHEMBL18949434 | 0.87 | EGFR (0.55) | EGFRERBB2GAK | |
| SCHEMBL15222030 | 0.86 | EGFR (0.68) | EGFRERBB2 | |
| SCHEMBL14864929 | 0.85 | EGFR (0.74) | EGFRERBB2GAK | |
| SCHEMBL14864924 | 0.84 | EGFR (0.55) | EGFRERBB2GAK | |
| SCHEMBL18949427 | 0.82 | EGFR (0.58) | EGFRERBB2GAK | |
| SCHEMBL14864930 | 0.81 | EGFR (0.73) | EGFRERBB2 | |
| SCHEMBL2132745 | 0.81 | EGFR (0.82) | EGFRERBB2GAK | |
| SCHEMBL2132756 | 0.81 | EGFR (0.82) | EGFRERBB2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222620-A1 | CYANOQUINOLINE DERIVATIVES | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2017-09-27 | — | — | EP | disclosed |
| EP-2581372-A1 | CYANOQUINOLINE DERIVATIVES | Tianjin Hemay Bio-Tech Co., Ltd. (CN) | 2013-04-17 | — | — | EP | disclosed |