Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 4/20 | 0.82 |
| ▸ | MAPT | P10636 | 8/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436611 | 0.87 | NPC1 (0.64) | NPC1POLBMAPTALDH1A1KDM4E | |
| SCHEMBL9763027 | 0.86 | MEN1 (0.81) | NPC1POLBMAPTALDH1A1KDM4E | |
| SCHEMBL438110 | 0.81 | MAPT (0.70) | NPC1POLBMAPTALDH1A1KDM4E | |
| SCHEMBL245490 | 0.80 | MAPT (0.68) | NPC1POLBMAPTALDH1A1KDM4E | |
| SCHEMBL3261562 | 0.78 | MEN1 (1.00) | POLBMAPTALDH1A1KDM4EALOX15 | |
| SCHEMBL246344 | 0.77 | MAPT (0.67) | NPC1POLBMAPTALDH1A1KDM4E | |
| SCHEMBL240724 | 0.76 | MAPT (0.62) | NPC1POLBMAPTALDH1A1KDM4E | |
| SCHEMBL244828 | 0.75 | MEN1 (0.75) | POLBMAPTALDH1A1KDM4EALOX15 | |
| SCHEMBL14865047 | 0.74 | MAPT (1.00) | POLBMAPTALDH1A1KDM4EALOX15 | |
| SCHEMBL243664 | 0.73 | MEN1 (0.70) | POLBMAPTALDH1A1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581451-A1 | Compounds for inhibiting mammalian s-nitrosoglutathione reductase | Indiana University Research and Technology Corporation (US) | 2013-04-17 | — | — | EP | disclosed |