Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.31 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.31 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186010 | 0.93 | BDKRB1 (0.39) | BDKRB1DDR1CTSLCTSKCNR2 | |
| SCHEMBL186879 | 0.92 | BDKRB1 (0.44) | BDKRB1DHODHEPHB2DDR1DDR2 | |
| SCHEMBL2809999 | 0.88 | BDKRB1 (0.36) | BDKRB1DHODHCNR2 | |
| SCHEMBL185964 | 0.88 | BDKRB1 (0.36) | BDKRB1DHODHCNR2 | |
| SCHEMBL13128560 | 0.87 | BDKRB1 (0.39) | BDKRB1CTSLCTSSCTSKCNR2 | |
| SCHEMBL185700 | 0.86 | CNR2 (0.38) | BDKRB1DDR1CNR2 | |
| SCHEMBL2808203 | 0.86 | CNR2 (0.38) | BDKRB1DDR1CNR2 | |
| Hydrochloric Acid SCHEMBL2813916 | 0.86 | BDKRB1 (0.39) | BDKRB1CTSLCTSSCTSKCNR2 | |
| SCHEMBL185957 | 0.85 | BDKRB1 (0.39) | BDKRB1CNR2 | |
| SCHEMBL185507 | 0.85 | BDKRB1 (0.38) | BDKRB1DHODHEPHB2DDR1DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |