SCHEMBL14865351

SCHEMBL14865351

CN(O)C(=O)c1cc2c(n(CCCC(F)(F)F)c1=O)CCCCCC2

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.56
CNR1 P21554 15/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5508849 0.86 CNR2 (0.57) CNR2CNR1
SCHEMBL14865324 0.86 CNR2 (0.74) CNR2CNR1
SCHEMBL14865335 0.85 CNR2 (0.69) CNR2CNR1
SCHEMBL5511938 0.84 CNR2 (0.60) CNR2CNR1
SCHEMBL11922653 0.83 CNR2 (0.58) CNR2CNR1
SCHEMBL5512494 0.83 CNR2 (0.77) CNR2CNR1
SCHEMBL14865355 0.81 CNR2 (0.66) CNR2CNR1
SCHEMBL14865330 0.78 CNR2 (0.65) CNR2CNR1
SCHEMBL216352 0.72 CNR2 (0.79) CNR2CNR1
SCHEMBL5519322 0.72 CNR2 (0.62) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1806342-B1 3-CARBAMOYL-2-PYRIDONE DERIVATIVE SHIONOGI & CO (JP) 2013-04-17 EP disclosed