Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185565 | 0.72 | STK17A (0.34) | — | |
| SCHEMBL31212827 | 0.63 | — | — | |
| SCHEMBL668445 | 0.63 | — | — | |
| SCHEMBL23603879 | 0.62 | NMT1 (0.32) | — | |
| SCHEMBL19209562 | 0.62 | MEN1 (0.37) | — | |
| SCHEMBL20659323 | 0.62 | TAAR1 (0.34) | — | |
| SCHEMBL30975524 | 0.62 | MEN1 (0.37) | — | |
| SCHEMBL28189536 | 0.62 | MAPT (0.32) | — | |
| Hydrochloric Acid SCHEMBL249520 | 0.61 | GBA1 (0.44) | GBA1 | |
| Hydrochloric Acid SCHEMBL30786192 | 0.61 | GBA1 (0.44) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |