Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.63 |
| ▸ | CNR1 | P21554 | 15/20 | 0.63 |
| ▸ | FAAH | O00519 | 5/20 | 0.45 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5514468 | 0.87 | CNR2 (0.67) | CNR2CNR1FAAHABHD12ABHD6 | |
| SCHEMBL11922842 | 0.87 | CNR2 (0.67) | CNR2CNR1FAAHABHD12KDM4E | |
| SCHEMBL5509529 | 0.87 | CNR2 (0.66) | CNR2CNR1FAAHABHD12ABHD6 | |
| SCHEMBL14215467 | 0.83 | CNR2 (0.61) | CNR2CNR1FAAHABHD12MAPT | |
| SCHEMBL2745641 | 0.83 | CNR2 (0.64) | CNR2CNR1FAAHABHD12KDM4E | |
| SCHEMBL5517486 | 0.83 | CNR2 (0.57) | CNR2CNR1FAAHABHD12ABHD6 | |
| SCHEMBL2747862 | 0.83 | CNR2 (0.57) | CNR2CNR1FAAHABHD12ABHD6 | |
| SCHEMBL5523764 | 0.80 | CNR2 (0.56) | CNR2CNR1FAAHKDM4EALDH1A1 | |
| SCHEMBL2746162 | 0.80 | CNR2 (0.83) | CNR2CNR1FAAHABHD12ABHD6 | |
| SCHEMBL27660212 | 0.80 | CNR2 (0.56) | CNR2CNR1FAAHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |