SCHEMBL14865386

SCHEMBL14865386

CCCCn1c(CCC)c(C)cc(C(=O)N[C@H](C(=O)O)C(C)C)c1=O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 15/20 0.52
CNR1 P21554 8/20 0.52
PPARG P37231 2/20 0.39
PPARA Q07869 1/20 0.39
GAA P10253 1/20 0.38
ERAP2 Q6P179 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5518058 0.92 CNR2 (0.61) CNR2CNR1PPARGPPARAERAP2
SCHEMBL14865396 0.92 CNR2 (0.61) CNR2CNR1PPARGPPARAERAP2
SCHEMBL5522058 0.89 CNR2 (0.48) CNR2CNR1PPARGPPARAGAA
SCHEMBL5524174 0.88 CNR2 (0.59) CNR2CNR1PPARGPPARA
SCHEMBL5515971 0.88 CNR2 (0.59) CNR2CNR1PPARGPPARA
SCHEMBL11920671 0.88 CNR2 (0.61) CNR2CNR1
SCHEMBL5524740 0.86 CNR2 (0.46) CNR2CNR1PPARGPPARAGAA
SCHEMBL5516035 0.83 CNR2 (0.54) CNR2CNR1PPARGPPARA
SCHEMBL2746975 0.82 CNR2 (0.56) CNR2CNR1
SCHEMBL5524796 0.81 CNR2 (0.47) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1806342-B1 3-CARBAMOYL-2-PYRIDONE DERIVATIVE SHIONOGI & CO (JP) 2013-04-17 EP disclosed