Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522923 | 0.96 | CNR2 (0.43) | CNR2CNR1ALDH1A1KMT2AALOX15 | |
| SCHEMBL5518874 | 0.80 | CNR2 (0.50) | CNR2CNR1ALDH1A1KMT2ANPC1 | |
| SCHEMBL5519124 | 0.77 | CNR2 (0.41) | CNR2CNR1ALDH1A1KMT2AALOX15 | |
| SCHEMBL14865409 | 0.76 | HTT (0.47) | ALDH1A1KMT2AALOX15NPC1KDM4E | |
| SCHEMBL11922863 | 0.71 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL5520743 | 0.71 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL5525198 | 0.70 | CNR2 (0.53) | CNR2CNR1NPC1 | |
| SCHEMBL5522763 | 0.70 | CNR2 (0.51) | CNR2CNR1KMT2AMEN1NPSR1 | |
| SCHEMBL2745669 | 0.69 | CNR2 (0.50) | CNR2CNR1ALDH1A1KDM4EHTT | |
| SCHEMBL5515502 | 0.68 | CNR2 (0.61) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |