Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811476 | 0.94 | BDKRB1 (0.35) | OPRL1BDKRB1CNR2RIPK1HDAC1 | |
| SCHEMBL2811472 | 0.94 | BDKRB1 (0.35) | OPRL1BDKRB1CNR2RIPK1HDAC1 | |
| Hydrochloric Acid SCHEMBL2806804 | 0.94 | BDKRB1 (0.35) | OPRL1BDKRB1CNR2HDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL2806801 | 0.94 | BDKRB1 (0.35) | OPRL1BDKRB1CNR2HDAC1HDAC3 | |
| SCHEMBL2807036 | 0.93 | BDKRB1 (0.36) | OPRL1BDKRB1CNR2MAPK3 | |
| SCHEMBL185952 | 0.93 | BDKRB1 (0.36) | OPRL1BDKRB1CNR2MAPK3 | |
| SCHEMBL185964 | 0.93 | BDKRB1 (0.36) | OPRL1BDKRB1CNR2RIPK1MAPK3 | |
| SCHEMBL2809999 | 0.93 | BDKRB1 (0.36) | OPRL1BDKRB1CNR2RIPK1MAPK3 | |
| SCHEMBL13128639 | 0.90 | BDKRB1 (0.40) | OPRL1BDKRB1CNR2HDAC1HDAC3 | |
| SCHEMBL2808175 | 0.89 | BDKRB1 (0.36) | OPRL1BDKRB1CNR2RIPK1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |