SCHEMBL14865401

SCHEMBL14865401

CCCCn1c(CCC)c(CC)cc(C(=O)N[C@@H](CC(C)CC)C(=O)O)c1=O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 18/20 0.46
CNR1 P21554 11/20 0.46
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5522290 0.93 CNR2 (0.47) CNR2CNR1MAPT
SCHEMBL14865438 0.90 CNR2 (0.47) CNR2CNR1
SCHEMBL5515502 0.85 CNR2 (0.61) CNR2CNR1
SCHEMBL5524796 0.84 CNR2 (0.47) CNR2CNR1
SCHEMBL5522058 0.84 CNR2 (0.48) CNR2CNR1
SCHEMBL5520869 0.84 CNR2 (0.52) CNR2CNR1
SCHEMBL2754917 0.83 CNR2 (0.48) CNR2CNR1
SCHEMBL5517623 0.83 CNR2 (0.48) CNR2CNR1
SCHEMBL27680186 0.82 CNR2 (0.56) CNR2CNR1
SCHEMBL5513474 0.81 CNR2 (0.48) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1806342-B1 3-CARBAMOYL-2-PYRIDONE DERIVATIVE SHIONOGI & CO (JP) 2013-04-17 EP disclosed