Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCND2 | P30279 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGAV | P06756 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525406 | 0.92 | CNR2 (0.41) | GCKHDAC1CNR2CNR1P4HTM | |
| SCHEMBL5525887 | 0.83 | GCK (0.48) | GCKHDAC1CNR2CNR1P4HTM | |
| SCHEMBL11922994 | 0.74 | GCK (0.45) | GCKCNR2CNR1ADORA3ADORA2B | |
| SCHEMBL5521460 | 0.69 | CNR2 (0.45) | CNR2CNR1ADORA3ADORA2BADORA2A | |
| SCHEMBL5517181 | 0.67 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL5519135 | 0.67 | CNR2 (0.45) | CNR2CNR1MAPTRXFP1KDM4E | |
| SCHEMBL5509889 | 0.65 | CNR2 (0.49) | CNR2CNR1MAPTKDM4E | |
| SCHEMBL14865454 | 0.64 | PLA2G10 (0.38) | CNR2CNR1 | |
| SCHEMBL14472357 | 0.61 | CNR2 (0.44) | CNR2CNR1MAPTRXFP1KDM4E | |
| SCHEMBL10661608 | 0.60 | P4HTM (0.62) | HDAC1P4HTMMAPTDPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |