Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.53 |
| ▸ | CNR1 | P21554 | 12/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746852 | 0.80 | CNR2 (0.66) | CNR2CNR1USP2CYP3A4CYP2D6 | |
| SCHEMBL5517661 | 0.79 | CNR2 (0.61) | CNR2CNR1NLRP3 | |
| SCHEMBL2746581 | 0.79 | CNR2 (0.61) | CNR2CNR1NLRP3 | |
| SCHEMBL5523964 | 0.75 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL5524770 | 0.74 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL2746529 | 0.74 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL14865404 | 0.73 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL5524798 | 0.71 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL2746039 | 0.70 | CNR2 (0.56) | CNR2CNR1 | |
| SCHEMBL2746668 | 0.70 | CNR1 (0.60) | CNR2CNR1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |