Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 8/20 | 0.68 |
| ▸ | CNR1 | P21554 | 9/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764514 | 0.88 | BDKRB1 (0.67) | BDKRB1CNR1 | |
| SCHEMBL2808158 | 0.86 | BDKRB1 (0.61) | BDKRB1CNR1 | |
| SCHEMBL3652769 | 0.83 | BDKRB1 (0.74) | BDKRB1CNR1 | |
| SCHEMBL3649078 | 0.83 | BDKRB1 (0.74) | BDKRB1CNR1 | |
| SCHEMBL3798079 | 0.81 | BDKRB1 (0.59) | BDKRB1CNR1 | |
| SCHEMBL3798069 | 0.81 | BDKRB1 (0.59) | BDKRB1CNR1 | |
| SCHEMBL765554 | 0.80 | BDKRB1 (0.67) | BDKRB1CNR1 | |
| SCHEMBL13908489 | 0.79 | BDKRB1 (1.00) | BDKRB1CNR1 | |
| SCHEMBL13908646 | 0.78 | BDKRB1 (1.00) | BDKRB1CNR1 | |
| SCHEMBL765602 | 0.78 | BDKRB1 (0.63) | BDKRB1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |