Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520940 | 0.89 | CNR2 (0.44) | CNR1CNR2PPARGMAPTALDH1A1 | |
| SCHEMBL14865403 | 0.82 | CNR2 (0.50) | CNR1CNR2ALDH1A1 | |
| SCHEMBL27660200 | 0.81 | TACR3 (0.47) | PPARGMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL5521700 | 0.81 | TACR3 (0.47) | PPARGMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL5516376 | 0.76 | KMT2A (0.47) | CNR1CNR2PPARGALDH1A1CA1 | |
| SCHEMBL11923131 | 0.75 | CNR2 (0.48) | CNR1CNR2PPARGKMT2AMEN1 | |
| SCHEMBL5516389 | 0.74 | MEN1 (0.48) | CNR1CNR2PPARGMAPTALDH1A1 | |
| SCHEMBL5522248 | 0.73 | CNR2 (0.50) | CNR1CNR2PPARGKMT2AMEN1 | |
| SCHEMBL2746633 | 0.73 | CNR2 (0.50) | CNR1CNR2PPARGKMT2AMEN1 | |
| SCHEMBL5524739 | 0.73 | ATM (0.52) | CNR1CNR2PPARGKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |