Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805903 | 0.90 | BDKRB1 (0.63) | BDKRB1CYP3A4CYP2C9CYP2C19NAMPT | |
| SCHEMBL14865428 | 0.89 | BDKRB1 (0.53) | BDKRB1CYP3A4CYP2C9CYP2C19NAMPT | |
| SCHEMBL2805104 | 0.89 | BDKRB1 (0.56) | BDKRB1CYP3A4CYP2C9CYP2C19NAMPT | |
| SCHEMBL13128626 | 0.88 | BDKRB1 (0.61) | BDKRB1CYP3A4CYP2C9CYP2C19NPC1 | |
| SCHEMBL764432 | 0.88 | BDKRB1 (0.61) | BDKRB1CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL2548562 | 0.83 | BDKRB1 (0.62) | BDKRB1CYP3A4CYP2C9CYP2C19NAMPT | |
| SCHEMBL2811075 | 0.82 | BDKRB1 (0.57) | BDKRB1NAMPTHDAC1MEN1KMT2A | |
| SCHEMBL13128624 | 0.82 | BDKRB1 (0.54) | BDKRB1CYP3A4CYP2C9CYP2C19NAMPT | |
| SCHEMBL2807548 | 0.81 | BDKRB1 (0.53) | BDKRB1CYP3A4CYP2C9CYP2C19NAMPT | |
| SCHEMBL2836906 | 0.80 | BDKRB1 (0.54) | BDKRB1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |