Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519135 | 0.93 | CNR2 (0.45) | CNR2CNR1AHRPTGDR2DEGS1 | |
| SCHEMBL5525887 | 0.78 | GCK (0.48) | CNR2CNR1AHRSORT1NPC1 | |
| SCHEMBL5517181 | 0.73 | CNR2 (0.47) | CNR2CNR1AHRNPC1RAB9A | |
| SCHEMBL5519124 | 0.70 | CNR2 (0.41) | CNR2CNR1NPC1KDM4EALDH1A1 | |
| SCHEMBL5525406 | 0.69 | CNR2 (0.41) | CNR2CNR1MAPTP4HTM | |
| SCHEMBL5509889 | 0.67 | CNR2 (0.49) | CNR2CNR1KDM4EALDH1A1MAPT | |
| SCHEMBL5519319 | 0.66 | CNR2 (0.45) | CNR2CNR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5516448 | 0.66 | CNR2 (0.47) | CNR2CNR1KDM4EALDH1A1POLB | |
| SCHEMBL5523137 | 0.65 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL5523022 | 0.65 | CNR1 (0.48) | CNR2CNR1PTGDR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |