Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.50 |
| ▸ | CNR1 | P21554 | 9/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523176 | 0.91 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL14679047 | 0.81 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL5517425 | 0.81 | CNR2 (0.67) | CNR2CNR1CXCR2 | |
| SCHEMBL5517414 | 0.81 | CNR2 (0.65) | CNR2CNR1ATM | |
| SCHEMBL11922999 | 0.78 | CNR2 (0.46) | CNR2CNR1LMNA | |
| SCHEMBL5518920 | 0.73 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL5525261 | 0.73 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL5521598 | 0.73 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL2746591 | 0.73 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL14679043 | 0.73 | CNR2 (0.83) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |