Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486896 | 1.00 | HDAC1 (0.64) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL722453 | 0.91 | HDAC1 (0.77) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL725551 | 0.91 | HDAC1 (0.77) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL1486937 | 0.89 | HDAC1 (0.76) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL1486935 | 0.89 | HDAC1 (0.76) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL1486946 | 0.82 | HDAC1 (0.80) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL1486943 | 0.82 | HDAC1 (0.80) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL12473984 | 0.82 | HDAC1 (0.83) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL1486863 | 0.82 | HDAC1 (0.74) | HDAC1KCNH2HDAC3HDAC4HDAC2 | |
| SCHEMBL1486862 | 0.82 | HDAC1 (0.74) | HDAC1KCNH2HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053925-A1 | Hydroxamate-Based Inhibitors of Deacetylases | NOVARTIS AG | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053925-A1 | Hydroxamate-Based Inhibitors of Deacetylases | HDAC1, HDAC11, HDAC3 | HDAC1 1/4885KCNH2 3415/4885HDAC3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.