Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12712224 | 0.94 | SMN1; SMN2 (0.50) | SMN1; SMN2TAOK1TAOK3CHRM4TAS1R3 | |
| SCHEMBL12713006 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2TAOK1TAOK3CHRM4TSHR | |
| SCHEMBL1238861 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2TAOK1TAOK3CHRM4TAS1R3 | |
| SCHEMBL1238858 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2TAOK1TAOK3CHRM4TAS1R3 | |
| SCHEMBL1238717 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2TAOK1TAOK3CHRM4TAS1R3 | |
| SCHEMBL1238767 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2TAOK1TAOK3TAS1R3TAS1R1 | |
| SCHEMBL1238719 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2TAOK1TAOK3CHRM4TAS1R3 | |
| SCHEMBL1238769 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2TAOK1TAOK3TAS1R3TAS1R1 | |
| SCHEMBL1240045 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2TAOK1TAOK3TAS1R3TAS1R1 | |
| SCHEMBL1240047 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2TAOK1TAOK3TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130095068-A1 | AGENT FOR TREATING HCV INFECTION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-04-18 | — | — | US | disclosed |
| US-20130095068-A1 | AGENT FOR TREATING HCV INFECTION | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130095068-A1 | AGENT FOR TREATING HCV INFECTION | EIF2AK2, IRF3, IFNAR1 | SMN1; SMN2 3982/4885TAOK1 2949/4885TAOK3 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.