Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 15/20 | 0.69 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.69 |
| ▸ | ATM | Q13315 | 9/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.69 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.69 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.69 |
| ▸ | ATR | Q13535 | 2/20 | 0.69 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.69 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.69 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | CSF1R | P07333 | 1/20 | 0.69 |
| ▸ | MET | P08581 | 1/20 | 0.69 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.69 |
| ▸ | LTK | P29376 | 1/20 | 0.69 |
| ▸ | CDK7 | P50613 | 1/20 | 0.69 |
| ▸ | NEK2 | P51955 | 1/20 | 0.69 |
| ▸ | JAK3 | P52333 | 1/20 | 0.69 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL928267 | 0.91 | MTOR (0.76) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14872905 | 0.90 | MTOR (0.71) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14872954 | 0.90 | PIK3CA (0.69) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14872809 | 0.89 | MTOR (0.69) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14872826 | 0.88 | PIK3CA (0.67) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14872889 | 0.87 | PIK3CA (0.71) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14872907 | 0.86 | PIK3CA (0.70) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14872789 | 0.85 | PIK3CA (0.64) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14872960 | 0.84 | MTOR (0.68) | MTORPIK3CAATMPIK3CDPIK3CG | |
| SCHEMBL14873038 | 0.84 | PIK3CA (0.77) | MTORPIK3CAATMPIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013053273-A1 | IMIDAZO QUINOLINE DERIVATIVE AND MEDICINAL SALT THEREOF, PREPARATION METHOD THEREOF AND USE IN MEDICINE THEREOF | 上海恒瑞医药有限公司 (CN) | 2013-04-18 | — | — | WO | disclosed |