Ethylenediamine

Ethylenediamine

SCHEMBL1487301

NCCN.O=S(=O)(O)CCCCS(=O)(=O)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A known ✓ P27815 1/20 0.43
APP P05067 1/20 0.78
LMNA P02545 4/20 0.67
BLM P54132 3/20 0.67
SLC6A6 P31641 1/20 0.67
CYP2C19 P33261 1/20 0.67
PTGS1 P23219 1/20 0.43
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
PMP22 Q01453 2/20 0.38
TSHR P16473 2/20 0.38
GMNN O75496 2/20 0.38
THPO P40225 2/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
HBB P68871 1/20 0.38
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
NT5E P21589 1/20 0.33
CA4 P22748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL513009 0.91
SCHEMBL513074 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19
SCHEMBL9386346 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19
Ammonia Solution, Strong SCHEMBL17272370 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19
SCHEMBL9387197 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19
SCHEMBL5955499 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19
SCHEMBL9390750 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19
SCHEMBL6047710 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19
SCHEMBL9387343 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19
SCHEMBL8962050 0.88 APP (0.79) APPLMNABLMSLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010906-A1 ACID STIMULATION METHODS SCHLUMBERGER TECHNOLOGY CORP (US) 2024-01-11 US claimed
US-11767465-B2 Acid stimulation methods SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2023-09-26 US claimed
US-20220195286-A1 ACID STIMULATION METHODS SCHLUMBERGER TECHNOLOGY CORPORATION 2022-06-23 US claimed
WO-2020219629-A9 ACID STIMULATION METHODS SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2021-11-04 WO claimed
WO-2020219629-A1 ACID STIMULATION METHODS SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2020-10-29 WO claimed
US-6417323-B1 RING-OPENING POLYMERIZATION OF SUBSTITUTED EPOXIDE IN RARE EARTH COMPOUND AND REDUCING AGENT PRESENCE; ETHERIFICATION KAO CORPORATION (JP) 2002-07-09 US claimed
WO-2024020339-A1 APPLICATION OF ORGANIC OXIDIZER AND ENZYME COMBINATION AS BREAKER FLUID FOR FILTER CAKE CLEANUP SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2024-01-25 WO disclosed
US-20240010906-A1 ACID STIMULATION METHODS SCHLUMBERGER TECHNOLOGY CORP (US) 2024-01-11 US disclosed
US-20230392065-A1 MONOVALENT BRINE-BASED RESERVOIR DRILLING FLUID SCHLUMBERGER TECHNOLOGY CORP (US) 2023-12-07 US disclosed
US-11820934-B2 Microsphere compositions and methods for production in oil-based drilling fluids SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2023-11-21 US disclosed
US-11795369-B2 Crosslinked synthetic polymer-based reservoir drilling fluid SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2023-10-24 US disclosed
US-11767465-B2 Acid stimulation methods SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2023-09-26 US disclosed
US-11767457-B2 Monovalent brine-based reservoir drilling fluid SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2023-09-26 US disclosed
US-6906167-B2 Metathesis ring-opening polymerization using epoxides; using rare earth metal catalyst and reducing agent KAO CORPORATION (JP) 2005-06-14 US disclosed
US-20050004344-A1 Process for producing polyether KAO CORPORATION (JP) 2005-01-06 US disclosed
US-6800723-B2 EPOXY RESINS FORMED VIA CATALYTIC METHATHESIS RING-OPENING POLYMERIZATION WITH RARE EARTH METAL COMPLEX KAO CORPORATION (JP) 2004-10-05 US disclosed
EP-1057845-B1 PROCESS FOR PRODUCING POLYETHER KAO CORP (JP) 2004-01-21 EP disclosed
US-20020151674-A1 Epoxy resins formed via catalytic methathesis ring-opening polymerization with rare earth metal complex KAO CORPORATION (JP) 2002-10-17 US disclosed
US-6417323-B1 RING-OPENING POLYMERIZATION OF SUBSTITUTED EPOXIDE IN RARE EARTH COMPOUND AND REDUCING AGENT PRESENCE; ETHERIFICATION KAO CORPORATION (JP) 2002-07-09 US disclosed
EP-1057845-A1 PROCESS FOR PRODUCING POLYETHER Kao Corporation (JP) 2000-12-06 EP disclosed