SCHEMBL14873241 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK1	P28482	14/20	0.47

▸	MAPK3	P27361	9/20	0.47

▸	ALDH1A1	P00352	1/20	0.42

▸	POLB	P06746	1/20	0.42

▸	MAPT	P10636	1/20	0.42

▸	HPGD	P15428	1/20	0.42

▸	CSNK1D	P48730	1/20	0.42

▸	L3MBTL1	Q9Y468	2/20	0.40

▸	TTK	P33981	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14863425	0.85	MAPK1 (0.48)	MAPK1MAPK3ALDH1A1POLBMAPT
SCHEMBL14863426	0.85	MAPK1 (0.48)	MAPK1MAPK3ALDH1A1POLBMAPT
SCHEMBL18108519	0.79	PDE4A (0.47)	MAPK1MAPK3MAPTHPGD
SCHEMBL14863473	0.76	MAPK1 (0.50)	MAPK1MAPK3TTK
SCHEMBL14863472	0.76	MAPK1 (0.50)	MAPK1MAPK3TTK
SCHEMBL4781046	0.76	JAK2 (0.48)	MAPK1MAPK3ALDH1A1POLBMAPT
SCHEMBL14873314	0.75	MAPK1 (0.50)	MAPK1MAPK3TTK
SCHEMBL15476719	0.75	MAPK1 (0.50)	MAPK1MAPK3TTK
SCHEMBL18108614	0.74	AURKA (0.59)	—
SCHEMBL21012193	0.74	AURKA (0.50)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013053051-A1	INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME	UNIVERSITY HEALTH NETWORK (CA)	2013-04-18	—	—	WO	disclosed