Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.78 |
| ▸ | HTR2B | P41595 | 8/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228609 | 0.87 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL14874790 | 0.83 | HTR2C (0.75) | HTR2CHTR2B | |
| SCHEMBL14874775 | 0.82 | HTR2C (0.74) | HTR2CHTR2B | |
| SCHEMBL6582412 | 0.80 | HTR2C (0.59) | HTR2CHTR2BHTR2A | |
| SCHEMBL14874822 | 0.80 | HTR2C (0.74) | HTR2CHTR2BHTR2A | |
| SCHEMBL14874820 | 0.80 | HTR2C (0.74) | HTR2CHTR2BHTR2A | |
| SCHEMBL14874859 | 0.76 | HTR2C (0.76) | HTR2CHTR2BHTR2A | |
| SCHEMBL14874784 | 0.76 | HTR2C (0.61) | HTR2CHTR2BHTR2A | |
| SCHEMBL14874715 | 0.75 | HTR2C (0.73) | HTR2CHTR2BHTR2A | |
| SCHEMBL14874760 | 0.75 | HTR2C (0.62) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108649-B1 | Novel indol carboxylic acid bispyridyl carboxamide derivatives as 5-HT2c receptor antagonists | KOREA RES INST CHEM TECH (KR) | 2013-04-24 | — | — | EP | claimed |