Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874994 | 0.88 | PDE10A (0.83) | PDE10A | |
| SCHEMBL2457944 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2459214 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2457759 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2461627 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2455751 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2459606 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL13362177 | 0.80 | PDE10A (0.83) | PDE10A | |
| SCHEMBL2460867 | 0.80 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2457663 | 0.80 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364306-B1 | Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors | AMGEN INC (US) | 2013-04-24 | — | — | EP | claimed |